Multivalent mannosides with inherent macrophage recognition abilities, built on β-cyclodextrin, RAFT cyclopeptide or peptide dendrimer cores, trigger selective inhibition of lysosomal β-glucocerebrosidase or α-mannosidase depending on valency and topology, offering new opportunities in multitargeted drug design. s/press release
Manuel González-Cuesta‡ a, David Goyard† b, Eiji Nanba c, Katsumi Higaki c, José M. García Fernández *d, Olivier Renaudet *be and Carmen Ortiz Mellet *a
Chem. Commun., 2019, 55, 12845-12848 DOI: 10.1039/C9CC06376E
